Several studies have shown that the use of Actemra may have negative effects on your heart and other bodily functions. This includes high cholesterol, stroke, heart attacks, serious infections, GI perforations, and other problems.
High cholesterol
Taking Actemra can increase your risk of having a hole in your stomach or intestines. You should talk to your doctor before taking Actemra Side Effects if you have a history of ulcers or diverticulitis.
Actemra also increases your risk of certain cancers. The FDA has issued a boxed warning, which warns patients and doctors about the risks of this drug. In addition, it can make a current infection worse.
If you are taking Actemra and have an infection, your healthcare provider may stop the medication. It is also important to keep track of your symptoms. If you have a fever, you may want to talk to your doctor. A CT scan or X-ray may be needed.
Actemra may interact with several other drugs. It can also cause allergic reactions, which can be severe and life-threatening.
Actemra is not suitable for women who are pregnant or breastfeeding. It also interacts with drugs that weaken the immune system. Other drugs that can affect Actemra include cyclosporine, sirolimus, and blood thinners.
Actemra can cause serious infections, which can include infections caused by fungi and tuberculosis. Actemra can also damage the protective covering around nerves. If you take Actemra and are diagnosed with an infection, you may need to stay in the hospital.
Actemra may also cause serious cardiovascular conditions, including a heart attack. In a study, patients taking Actemra were found to have a greater risk of heart failure and stroke than patients on other drugs.
People with a history of heart failure, stroke, or high cholesterol should not take Actemra. People with low neutrophil counts should not take Actemra. Actemra has been linked to a higher risk of lung problems, including interstitial lung disease.
GI perforations
GI perforations are an uncommon adverse event, but they are still a risk. They can lead to gastrointestinal peritonitis and internal bleeding. Depending on the size and nature of the hole, recovery can vary.
It’s important to remember that GI perforations are often treated with surgery. However, some etiologies are amenable to a nonsurgical approach. Several factors can increase the risk of GI perforation, including smoking, obesity, and alcohol consumption. There is a risk of perforation in people with rheumatoid arthritis. The risk increases with age and increases with the duration of treatment.
The rate of gastrointestinal perforations due to Actemra is relatively small. It’s estimated that about one in a hundred people who take the drug will experience one. It’s also estimated that women are four times more likely to experience GI perforations than men.
Tocilizumab, an anti-TNF-a agent, has been associated with lower GI perforations. Its risk is about twice that of TNFi therapy.
Tofacitinib, another Janus kinase inhibitor, has been associated with lower GI perforations as well. In addition, tocilizumab has been associated with an increased risk of GIP.
As with any drug, there are common side effects to Actemra. It’s important to talk to your doctor about any new abdominal symptoms you experience. If the symptoms persist, talk to your doctor about whether or not you should take the drug. It’s also important to know the side effects of other medications you are taking.
The most common symptoms include abdominal pain, nausea, diarrhea, and vomiting. A blood test can also help diagnose the presence of an infection. These symptoms are often followed by abdominal pain.
GI perforations can lead to more serious health complications, such as sepsis and organ failure. It’s important to report any new abdominal symptoms to your doctor, especially if you take Actemra.
Serious infections
Taking Actemra can increase the risk of serious infections. Serious infections may include a wide range of infections, including bacterial, viral, and fungal infections. These can lead to hospitalization and possibly death.
Taking Actemra may increase your risk of getting a tuberculosis infection. Your healthcare provider may test for TB before you start taking Actemra. If you are diagnosed with TB, you may temporarily stop taking Actemra until the infection has been treated.
Although Actemra is not known to cause cardiovascular problems, it may worsen conditions that affect the nerves in your body. You may also experience clay-colored bowel movements or other side effects. Taking Actemra may also cause you to gain weight.
Actemra is used to treat a type of interstitial lung disease (ILD) called systemic sclerosis-immune limiting disease (SSc-ILD). SSc-ILD causes the lung tissue to thicken and harden, resulting in symptoms like shortness of breath.
Actemra may be prescribed for other conditions, but the FDA has warned that the drug may be associated with serious infections. Actemra has a black box warning that warns doctors and patients about the risk of getting serious infections while taking the drug.
The black box warning is the most serious type of warning. The FDA has investigated Actemra and other drugs in a series of safety reviews. The results of these reviews have led to a black box warning for Actemra that only mentions the risk of serious infections.
The FDA has also received over 1,000 reports of deaths from Actemra. Symptoms of serious infections include fever, chills, weight loss and fatigue. You may experience a cough and shortness of breath. Some infections may require you to go to the hospital, but others may not.
Heart attacks
Thousands of people are taking the rheumatoid arthritis drug Actemra, but the drug’s side effects have caused serious injuries and even death. Actemra has been linked to heart attacks, fatal brain bleeds, infections, and other serious medical issues. Several doctors have written about the drug’s potential role in these cases.
Researchers have found that Actemra users have a higher rate of heart failure than users of other rheumatoid arthritis drugs. Actemra users have a 1.5-times higher rate of heart failure than patients using Enbrel.
An investigation by STAT news, which analyzed more than half a million adverse event reports from rheumatoid arthritis medications, found that Actemra patients are at a higher risk for heart attack, stroke, and other serious life-threatening conditions. The study also found that the FDA Adverse Event Reporting System (FAERS) data – which is voluntary – only represents 10 percent of the actual adverse event reports.
The STAT study found that Actemra users had elevated blood lipids, which are believed to contribute to heart disease over time. Actemra patients also had elevated liver enzymes, which are associated with heart failure.
Another study found that Actemra patients were more likely to experience strokes, bowel perforation, and heart failure than patients who used other rheumatoid drugs. Actemra patients also had higher rates of pancreatitis and interstitial lung disease than other patients.
Actemra is the fifth highest-grossing drug on the market, earning more than $1.7 billion in sales in 2012. But it also carries higher rates of side effects than competitors. If you or a loved one has experienced serious side effects while taking Actemra, contact an attorney at Parker Waichman LLP as soon as possible.
Stroke
Several studies have shown that Actemra, rheumatoid arthritis (RA) drug, can cause problems in the heart, lungs, and other parts of the body. Some of these side effects can be deadly, so you need to know what to look out for.
For example, in a recent study of rheumatoid arthritis drugs, researchers found that Actemra was associated with a five percent increase in the risk of heart failure. In addition, patients on Actemra were shown to have elevated blood lipids. These elevated levels have been shown to cause heart problems over time.
A study analyzed more than 13,500 FAERS (FDA adverse event reports) reports. Researchers found that 0.4 percent of Actemra users were found to have pancreatitis. The study also found that 58 percent of Actemra users had interstitial lung disease.
The study also found that 29 percent of Actemra users had a heart attack within a month of taking the drug. It’s important to note that these side effects are common. Actemra users should contact their doctors if these symptoms persist. If you have suffered from an AcActemra-relatednjury, you may be eligible for compensation.
The study also found that Actemra was associated with more than half a million rheumatoid arthritis drug adverse event reports. In fact, Actemra accounted for 1.65 percent of all adverse event reports filed with the FDA.
The study also found that Actemra users were more likely to suffer from strokes. Researchers found that participants on Actemra were more likely to have a stroke, but it was not necessarily the most obvious or effective way to reduce the risk of a stroke.
Conclusion
The study also found that Actemra had a higher rate of side effects than other RA medications. A few of these side effects included gastrointestinal perforation.